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transdifferentiation
This term is a highly specialized technical descriptor used almost exclusively within cellular biology and regenerative medicine. It describes a specific mechanism of cellular plasticity where a cell switches its identity from one specialized type to another, bypassing the need to return to a stem-cell-like state. This distinguishes it from dedifferentiation, where a cell reverts to a simpler state, or reprogramming, which typically involves an intermediate pluripotent stage.
As a technical scientific term, it is treated as an uncountable noun when referring to the biological phenomenon or process in general. While it can occasionally be pluralized in specific experimental contexts to describe multiple distinct events of conversion, it is most frequently used in the singular to denote the concept itself.
Ý nghĩa
The biological process by which one mature somatic cell transforms into another mature somatic cell without undergoing an intermediate pluripotent state.
The researchers observed transdifferentiation when pancreatic cells were converted directly into insulin-producing beta cells.