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pernicious anemia

pernicious anemia
Danh từ

This term describes a specific autoimmune pathology where the stomach fails to produce intrinsic factor, a protein necessary for B12 absorption. The word "pernicious" here is used in its archaic medical sense meaning "deadly" or "destructive," reflecting the historical reality that the condition was fatal before the discovery of vitamin B12 therapy.

In modern clinical settings, it is distinguished from general vitamin B12 deficiency (which can be caused by diet or other malabsorption issues) by the presence of specific antibodies. Because it is a chronic medical diagnosis, it is treated as a singular clinical entity rather than a countable object.

Ý nghĩa

Danh từpernicious anemia

A chronic condition caused by a deficiency of vitamin B12 due to the body's inability to absorb it, often resulting from a lack of intrinsic factor in the stomach.

The patient was diagnosed with pernicious anemia and required lifelong vitamin B12 injections.

Từ liên quan

vitamin B12cobalaminstomachabsorptionileumerythrocytehemoglobinred blood cellwhite blood cellplateletpancytopeniafolatefolic acidperniciousdeficiencyautoimmuneantibodyparietal cellgastrinhematologybloodbone marrowerythropoiesisfatiguelethargydyspneapallorglossitisneuropathyparesthesiaataxiacognitive impairmentdementiamemory lossinjectioncyanocobalaminhydroxocobalaminsupplementationtherapydiagnosisbiopsyblood testperniciousnessmalabsorptiondigestionenzymeproteinamino acidmetabolismmyelindemyelinationspinal cordanemiaautoimmunityimmune systemgastritismucosaepitheliumhematopoietic stem cellreticulocytehemolysishypoxiaoxygenationtachycardiaweaknessvertigotinnituspsychosisdepressionirritability
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