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bone marrow failure
bone marrow failure
Danh từ
This term describes a critical hematological state where the hematopoietic system collapses, resulting in pancytopenia. It is a clinical diagnosis rather than a single disease, often serving as a manifestation of underlying conditions such as aplastic anemia, leukemia, or severe toxicity from chemotherapy.
In medical discourse, the term is used with high formality and precision. Because it describes a systemic physiological failure, it is treated as an uncountable condition in clinical contexts, referring to the state of the patient's marrow rather than a discrete event that can be counted.
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aplastic anemiapancytopeniahematopoiesisstem cellleukocyteerythrocytethrombocyteplatelethemoglobinanemialeukopeniathrombocytopeniabloodmarrowmyeloidlymphoidgranulocytemonocytebasophileosinophilneutrophillymphocyteplasmaserumcytopeniacytokinegrowth factortransfusiontransplantgraftdonorchemotherapyradiationtoxicityinfectionhemorrhagebruisefatiguepallorfeverimmunodeficiencyleukemiamyelodysplastic syndromemyelofibrosismyelomahematologyoncologybiopsyaspirationblood countwhite blood cellred blood cellbone marrowmedullastromahematopoietic stem cellproliferationdifferentiationapoptosissuppressionimmune systemautoimmunityantigenantibodycomplementhematocritreticulocyteblast cellmyeloblasterythroblastmegakaryocyte