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Trang chủTừ điểnPparalog

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paralog

paralog
Danh từ
Số nhiều: paralogs

This term is used exclusively within the fields of genetics and evolutionary biology to describe genes that arise from a duplication event. It is distinct from an ortholog, which refers to genes in different species that evolved from a common ancestral gene via speciation. Paralogs allow for evolutionary innovation because one copy of the gene can maintain the original function while the other evolves a new, specialized role.

In a technical context, paralogs are often categorized as in-paralogs or out-paralogs depending on whether the duplication occurred after or before a specific speciation event. The term is strictly scientific and is not used in general conversation or metaphorical contexts.

Ý nghĩa

Danh từparalog

A gene that is related to another gene by duplication within a single genome.

The researchers identified a paralog of the insulin receptor that functions in the brain.

Ví dụ

The researcher identified a paralog that had evolved a completely new function.

none

The researcher identified a paralog that had evolved a completely new function.

Is this gene an ortholog or a paralog?

School Life

Is this gene an ortholog or a paralog?

The presence of a paralog allows the original gene to maintain its primary role while the copy diverges.

none

The presence of a paralog allows the original gene to maintain its primary role while the copy diverges.

I wonder if this specific paralog is expressed in the liver.

Health

I wonder if this specific paralog is expressed in the liver.

We found that the paralog is highly conserved across different mammalian species.

none

We found that the paralog is highly conserved across different mammalian species.

Wait, so a paralog results from a duplication event within the same species?

School Life

Waitso a paralog results from a duplication event within the same species?

The protein encoded by the paralog shows a slight difference in binding affinity.

Health

The protein encoded by the paralog shows a slight difference in binding affinity.

This paralog likely emerged during the whole genome duplication event.

History

This paralog likely emerged during the whole genome duplication event.

The sequence alignment clearly shows that these two genes are paralogs.

none

The sequence alignment clearly shows that these two genes are paralogs.

Từ liên quan

orthologgenegenomeduplicationhomologyhomologmutationevolutiondivergenceproteinsequenceallelechromosomelociphylogenycladespeciationancestordescendantgeneticsbioinformaticsnucleotidecodonexonintrontranscriptiontranslationexpressionphenotypegenotypevariantpolymorphismredundancyspecializationsubfunctionalizationneofunctionalizationcopypolyploidyaneuploidyalignmentblastmotifdomaincatalysisenzymemetabolismpromoterenhancertransposonrecombinationcrossovermutation rateselectionadaptationconservationorthologyparalogy
Cập nhật lần cuối: May 2026Báo lỗi