Nota: A tradução desta entrada está atualmente em revisão de qualidade, portanto parte do conteúdo é exibida temporariamente apenas em inglês.
Este verbete ainda não foi traduzido para o seu idioma, portanto o original é exibido abaixo.
toxification
This term describes the active transformation of a substance into a poisonous state. It is primarily used in scientific, medical, and environmental contexts to describe a chemical change rather than the mere presence of a toxin. While toxicity refers to the degree of poison, toxification refers to the actual process of becoming toxic.
In pharmacology and toxicology, the word specifically highlights the paradoxical nature of metabolism where the body accidentally creates a harmful byproduct from a benign precursor. Because it describes a process or a state of change, it is treated as an uncountable mass noun and does not typically take a plural form.
Meanings
The biological process by which a non-toxic substance is converted into a toxic metabolite within a living organism.
Certain liver enzymes are responsible for the toxification of specific drugs during metabolism.
Examples
The accidental toxification of the water supply led to a citywide emergency.
Certain enzymes in the liver can cause the toxification of otherwise harmless compounds.
The villain planned the slow toxification of the kingdom's soil to destroy the crops.
We must study the toxification process to understand how this drug becomes harmful.
Is it possible that the metabolic toxification of this chemical is what caused the organ failure?
The report details the toxification of the local ecosystem by industrial runoff.
I wonder if this plant undergoes toxification when exposed to high levels of sulfur.
The researcher focused on the bioactivation and subsequent toxification of the pro-carcinogen.
The researcher focused on the bioactivation and subsequent toxification of the pro-carcinogen.