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protonation
This term is used exclusively within the technical registers of chemistry and biochemistry. It describes a specific acid-base reaction where a molecule acts as a Brønsted-Lowry base by accepting a proton. The process is often discussed in the context of pH changes, as the degree of protonation determines the electrical charge and subsequent biological activity or solubility of a substance.
In a laboratory or academic setting, the term is frequently paired with its opposite, deprotonation. Because it describes a chemical process or state, it is treated as an uncountable noun when referring to the general phenomenon, though it can be countable when referring to specific instances or types of protonation events in a molecular sequence.
Meanings
Examples
The protonation of the carbonyl oxygen activates the molecule for nucleophilic attack.
Wait, does the protonation happen before or after the addition step?
The reaction rate depends heavily on the degree of protonation of the catalyst.
I wonder if the protonation state of this amino acid residue affects the enzyme activity.
Protonation occurs when a base accepts a proton from an acid.
The mechanism involves the rapid protonation of the alcohol group.
Check if the pH is low enough to ensure complete protonation of the ligand.
The shift in the NMR spectrum indicates the protonation of the nitrogen atom.