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neofunctionalization
This term is a highly specialized technical descriptor used almost exclusively within evolutionary biology and genetics. It describes a specific outcome of gene duplication where the selective pressure on one copy is relaxed, permitting the accumulation of mutations that lead to a novel biological role.
Because it refers to a specific biological process, it is treated as an uncountable noun. It is typically used in academic papers or textbooks to contrast with subfunctionalization, where the original functions are split between the two duplicated genes rather than a new function being created.
Meanings
Examples
The researcher explained how neofunctionalization allows for the evolution of novel proteins.
Could this be a clear case of neofunctionalization after the gene duplication event?
Neofunctionalization occurs when one paralog evolves a function that provides a selective advantage.
Neofunctionalization occurs when one paralog evolves a function that provides a selective advantage.
I wonder if neofunctionalization is more common in plants than in mammals.
The paper argues that neofunctionalization drove the diversification of the enzyme family.
We must distinguish between subfunctionalization and neofunctionalization in our analysis.
We must distinguish between subfunctionalization and neofunctionalization in our analysis.
The ancestral gene was duplicated and then underwent neofunctionalization to create a new receptor.
It is fascinating how neofunctionalization can lead to entirely new biological capabilities.
It is fascinating how neofunctionalization can lead to entirely new biological capabilities.