Nota: A tradução desta entrada está atualmente em revisão de qualidade, portanto parte do conteúdo é exibida temporariamente apenas em inglês.
Este verbete ainda não foi traduzido para o seu idioma, portanto o original é exibido abaixo.
ligation
This term is used exclusively within technical medical and biological registers. In a clinical setting, it refers to the physical act of tying a vessel or duct, often associated with permanent procedures like tubal ligation. The tone is sterile and objective, devoid of the emotional weight often associated with the outcomes of such surgeries.
In molecular biology, the term shifts from a mechanical action to a biochemical reaction. Here, it describes the enzymatic bonding of nucleic acid strands. While the medical sense involves a physical knot or tie, the biological sense involves the formation of a covalent phosphodiester bond, though both share the core concept of joining two separate entities into one continuous structure.
Meanings
Examples
The surgeon performed a ligation of the artery to stop the bleeding.
Tubal ligation is a permanent method of birth control for women.
We need to ensure the ligation of the DNA fragments is complete before transformation.
Did the ligation work or are the plasmids still open circles?
The procedure requires precise ligation of the vessel to prevent leakage.
I wonder if the ligation efficiency was too low for this specific vector.
Ligation of the two strands occurs via the formation of a phosphodiester bond.
The patient requested a tubal ligation during her recovery from the C-section.