Nota: A tradução desta entrada está atualmente em revisão de qualidade, portanto parte do conteúdo é exibida temporariamente apenas em inglês.
Este verbete ainda não foi traduzido para o seu idioma, portanto o original é exibido abaixo.
integrin
This term is used exclusively within specialized biological and medical contexts, specifically in cell biology and pathology. It describes a family of proteins that act as the physical bridge between the intracellular cytoskeleton and the extracellular matrix, making it a technical term of art rather than a word for general conversation.
Because it refers to a specific class of proteins, it is treated as a countable noun in scientific literature. Researchers frequently discuss different "integrins" or "integrin subtypes" when referring to the various combinations of alpha and beta subunits that form these receptors.
Meanings
Examples
Integrins play a crucial role in the migration of white blood cells to sites of inflammation.
The professor explained how an integrin molecule bridges the extracellular matrix and the cytoskeleton.
The professor explained how an integrin molecule bridges the extracellular matrix and the cytoskeleton.
I wonder if this specific integrin is overexpressed in the tumor cells.
Binding of ligands to the integrin triggers a cascade of intracellular signaling events.
We need to analyze the integrin expression levels in these tissue samples.
The cell cannot adhere properly if the integrin function is inhibited.
Look at how the integrin alpha and beta subunits form a heterodimer.
Certain drugs target the integrin to prevent blood clotting during surgery.