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major histocompatibility complex
major histocompatibility complex
Noun
pl: major histocompatibility complexes
This term refers to a highly specialized genetic system that allows the immune system to distinguish between self and non-self. In a clinical context, it is the primary biological determinant in organ transplant compatibility, where a mismatch between the donor and recipient leads to graft rejection.
As a technical biological term, it is treated as a singular entity. While it describes a complex of multiple genes and proteins, it is typically used as a singular noun in scientific literature.
Meanings
Related Words
antigenantibodyalleleepitopeproteingenechromosomeleukocytelymphocyteT cellB cellcytokinereceptorimmune systemimmunityhistocompatibilitytransplantgraftrejectionautoimmunityinflammationpathogenvirusbacteriapeptidemoleculecellnucleuscytoplasmmembranegeneticspolymorphismheterozygosityhomozygosityhaplotypelocipresentationrecognitionactivationapoptosisphagocytosismacrophagedendritic cellnatural killer cellcomplementserologytypingscreeningcrossmatchdonorrecipientallograftautograftxenografttolerancehypersensitivityallergyvaccineimmunologybiochemistryproteomicsgenomicsmutationselectionevolutiondiversity