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haplotype
This term is used primarily in genetics and evolutionary biology to describe a specific combination of alleles on a single chromosome. It differs from a genotype, which refers to the total genetic makeup of an individual across both sets of chromosomes. Haplotypes are essential for mapping genetic diseases and tracing maternal or paternal lineages because they are inherited as a single block without being shuffled by recombination.
In a clinical or research setting, the word carries a highly technical register. It is almost never used in casual conversation and is typically paired with terms like "mapping," "diversity," or "analysis" to describe the study of population genetics.
Meanings
Examples
The researchers identified a specific haplotype associated with the disease.
The researchers identified a specific haplotype associated with the disease.
Does this haplotype appear in other populations as well?
The mitochondrial haplotype allows us to trace maternal lineage back thousands of years.
I wonder if this rare haplotype is the key to their resistance.
The forensic team compared the haplotype found at the crime scene with the suspect's DNA.
A single haplotype can contain multiple genetic markers.
We need to sequence the entire region to determine the exact haplotype.
The distribution of this haplotype suggests a common ancestor in East Asia.