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heparanase

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enzyme heparan sulfate extracellular matrix glycosaminoglycan proteoglycan basement membrane cleavage hydrolysis degradation metastasis angiogenesis inflammation cancer tumor invasion migration permeability endothelium vascular interstitial ligand receptor growth factor cytokine chemokine heparin sulfation disaccharide polysaccharide catalysis substrate inhibitor activation secretion protein peptide amino acid cell tissue matrix collagen laminin fibronectin elastin protease metalloproteinase cathepsin plasmin apoptosis proliferation signaling pathology biochemistry pharmacology therapy drug assay biomarker expression transcription translation phosphorylation glycosylation active site cofactor pH kinetics half-life clearance homeostasis

Last Updated: May 2026•Report an Error

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