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overdominance
This term is a specialized technical expression used almost exclusively within the fields of genetics and evolutionary biology. It describes a specific state of heterozygote advantage, where the hybrid offspring possesses a survival or reproductive edge over both pure-breeding parents. This concept is central to explaining why certain deleterious alleles, such as those causing sickle cell anemia, persist in a population despite being harmful in a homozygous state.
Because it refers to a specific biological mechanism or phenomenon, the word is treated as an uncountable noun. It does not refer to a countable object but rather to a genetic principle or a state of being. It is rarely used outside of academic, scientific, or medical discourse.
Meanings
Examples
The professor explained that overdominance occurs when the heterozygote is more fit than either homozygote.
The professor explained that overdominance occurs when the heterozygote is more fit than either homozygote.
Sickle cell trait is a classic example of overdominance in humans.
I wonder if this specific allele frequency is maintained by overdominance.
Does overdominance always lead to a stable genetic polymorphism in the population?
Does overdominance always lead to a stable genetic polymorphism in the population?
The research paper argues that overdominance provides a selective advantage in malaria endemic regions.
The research paper argues that overdominance provides a selective advantage in malaria endemic regions.
We must distinguish between simple dominance and the mechanism of overdominance.
Overdominance ensures that both alleles are preserved within the gene pool.
The fitness landscape suggests a peak associated with overdominance at this locus.