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posttranslational
This term is a specialized technical adjective used almost exclusively within biochemistry and molecular biology. It describes the critical window of time after a ribosome has finished synthesizing a polypeptide chain but before that protein becomes biologically active or reaches its final destination.
Usage is typically restricted to scientific literature, textbooks, and laboratory reports. It is frequently paired with nouns like modifications, processing, or folding to describe the chemical changes—such as phosphorylation or glycosylation—that determine a protein's ultimate function and structure.
Meanings
Examples
Phosphorylation is a common posttranslational modification that regulates enzyme activity.
Phosphorylation is a common posttranslational modification that regulates enzyme activity.
We need to determine if this protein undergoes any posttranslational processing in the Golgi apparatus.
We need to determine if this protein undergoes any posttranslational processing in the Golgi apparatus.
Wait, does this specific protein require posttranslational cleavage to become active?
The researcher focused on the posttranslational control of gene expression.
The researcher focused on the posttranslational control of gene expression.
I wonder if the posttranslational addition of sugar groups affects the protein stability.
Many hormones are synthesized as inactive precursors and require posttranslational modification.
The lecture today covers the various types of posttranslational modifications including ubiquitination.
The lecture today covers the various types of posttranslational modifications including ubiquitination.