Nota: A tradução desta entrada está atualmente em revisão de qualidade, portanto parte do conteúdo é exibida temporariamente apenas em inglês.
Este verbete ainda não foi traduzido para o seu idioma, portanto o original é exibido abaixo.
intermediate filament
This term refers to a specific class of cytoskeletal elements characterized by their toughness and stability. Unlike microtubules or microfilaments, which are dynamic and frequently disassemble, these fibers are designed for long-term mechanical endurance, acting as the primary stress-absorbers of the cell.
In a clinical context, mutations affecting these proteins often lead to severe tissue fragility, such as in the skin or muscles, because the cell loses its ability to resist physical shearing forces.
Meanings
Examples
The intermediate filament network provides the cell with mechanical strength.
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Trivia
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Unlike microtubules, an intermediate filament is not polar.
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