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paxillin
Paxillin is a specialized protein used almost exclusively in cellular biology and biochemistry. It functions as a molecular scaffold, meaning it does not catalyze reactions itself but provides a physical structure that brings other proteins together to facilitate cell signaling and movement.
As a technical term for a specific protein, it is treated as an uncountable mass noun in scientific literature. Researchers refer to the presence, expression, or localization of paxillin rather than counting individual molecules of the protein.
Meanings
Examples
Paxillin is essential for the formation of focal adhesions in migrating cells.
The researcher noted that paxillin localization shifted toward the cell periphery.
The researcher noted that paxillin localization shifted toward the cell periphery.
Does the phosphorylation of paxillin trigger the disassembly of the adhesion complex?
Does the phosphorylation of paxillin trigger the disassembly of the adhesion complex?
I wonder if knocking down paxillin will inhibit the metastatic potential of these cancer cells.
Paxillin acts as a scaffold protein to recruit FAK to the plasma membrane.
We observed a significant increase in paxillin expression in the invasive cell line.
The interaction between paxillin and vinculin is critical for stabilizing the cytoskeleton.
The interaction between paxillin and vinculin is critical for stabilizing the cytoskeleton.
Look at the fluorescence image; paxillin is clearly concentrated at the leading edge.
Look at the fluorescence image; paxillin is clearly concentrated at the leading edge.