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proline
Proline is a specialized amino acid distinguished by its unique cyclic structure, which prevents it from acting as a typical hydrogen bond donor in protein backbones. This structural rigidity forces the polypeptide chain to bend, making it indispensable for the triple-helix architecture of collagen, the primary structural protein in connective tissues.
In a laboratory or clinical context, the term is used strictly as a chemical designation. Because it is a specific molecular entity, it is treated as an uncountable mass noun when referring to the substance in general, though it may be counted when referring to specific derivatives or salts of the amino acid.
Meanings
Examples
Proline is essential for the synthesis of collagen in the body.
The cyclic structure of proline causes a bend in the protein chain.
I wonder if increasing my proline intake will help my joint recovery.
Wait, is proline considered a non-essential amino acid?
The researcher analyzed the concentration of proline in the sample.
The researcher analyzed the concentration of proline in the sample.
Proline plays a key role in maintaining the integrity of connective tissues.
Did you know that proline is often called an imino acid?
The peptide sequence contains a high percentage of proline.
The peptide sequence contains a high percentage of proline.