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basolateral
This term is a specialized anatomical descriptor used almost exclusively in histology and cell biology. It describes a specific surface of epithelial cells, distinguishing it from the apical surface, which faces the lumen or external environment. The term combines basal (the bottom) and lateral (the sides), indicating a continuous membrane area that wraps around the cell's base and flanks.
Because it is a technical scientific term, it is used in a formal, academic register. It typically appears in descriptions of cellular transport, ion channels, and membrane proteins, where the precise location of a protein is critical to understanding how substances move across a tissue layer.
Meanings
Examples
The sodium potassium pump is primarily located on the basolateral membrane.
Wait, did you check if the receptor is expressed on the basolateral side?
Glucose is transported across the basolateral membrane into the bloodstream.
I wonder if the protein shifts from the apical to the basolateral surface during differentiation.
The basolateral domain of the cell interacts directly with the basement membrane.
We need to isolate the basolateral proteins for this assay.
Water moves through the basolateral space via osmotic gradients.
The tight junctions prevent proteins from diffusing from the apical to the basolateral region.