Nota: A tradução desta entrada está atualmente em revisão de qualidade, portanto parte do conteúdo é exibida temporariamente apenas em inglês.
Este verbete ainda não foi traduzido para o seu idioma, portanto o original é exibido abaixo.
polyclonal
This term is a specialized technical descriptor used almost exclusively within immunology and molecular biology. It describes a diverse population of antibodies that target multiple different epitopes on a single antigen, creating a broad but less specific immune response compared to monoclonal counterparts.
In a laboratory setting, the term carries a connotation of breadth and versatility. While monoclonal antibodies are prized for their surgical precision, polyclonal antibodies are often preferred for their ability to detect a protein regardless of slight variations in its structure or the presence of different conformational states.
Meanings
Examples
The researcher used polyclonal antibodies to detect multiple epitopes on the target protein.
We should use a polyclonal approach here to ensure we capture all variations of the antigen.
Polyclonal B cells produce a diverse range of antibodies that recognize different parts of the same pathogen.
Polyclonal B cells produce a diverse range of antibodies that recognize different parts of the same pathogen.
I wonder if the polyclonal response is strong enough to neutralize the virus effectively.
The serum contains a polyclonal mixture of immunoglobulins derived from the immunized rabbit.
Is this a monoclonal or a polyclonal antibody kit?
Is this a monoclonal or a polyclonal antibody kit?
The patient exhibited a strong polyclonal activation of lymphocytes during the acute phase of infection.
The patient exhibited a strong polyclonal activation of lymphocytes during the acute phase of infection.