Nota: A tradução desta entrada está atualmente em revisão de qualidade, portanto parte do conteúdo é exibida temporariamente apenas em inglês.
Este verbete ainda não foi traduzido para o seu idioma, portanto o original é exibido abaixo.
aneuploid
This term is a specialized technical descriptor used almost exclusively in genetics, cytology, and oncology. It describes a specific chromosomal imbalance where the total number of chromosomes is not an exact multiple of the haploid set, distinguishing it from polyploidy, where entire sets of chromosomes are duplicated.
In a clinical context, the term often carries a negative connotation, as aneuploidy is frequently associated with genetic disorders, such as Down syndrome, or the genomic instability characteristic of malignant cancer cells. It is used as a precise diagnostic label rather than a general descriptive term.
Meanings
Examples
The patient was found to be aneuploid for chromosome 21.
Is this cell line aneuploid or is it a stable diploid line?
Many cancer cells become aneuploid during rapid proliferation.
I wonder if the embryo is aneuploid based on these screening results.
The researcher noted that the yeast strains were aneuploid.
An aneuploid genome often leads to severe developmental defects.
We need to determine if the sample is aneuploid before proceeding with the experiment.
The karyotype clearly shows that the cells are aneuploid.