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vimentin
Vimentin is a specialized protein used primarily in histology and pathology to identify the origin of cells. It serves as a definitive biomarker for mesenchymal cells, making it indispensable for diagnosing sarcomas or identifying the process of epithelial-mesenchymal transition (EMT) in carcinomas.
As a biochemical substance and a specific type of protein, it is treated as an uncountable noun. It is referred to as a mass noun in scientific literature, meaning it does not have a plural form in standard biological contexts.
Meanings
A type of intermediate filament protein found in the cytoskeleton of mesenchymal cells, providing structural support and mechanical resistance to the cell.
The expression of vimentin is often used as a marker for epithelial-mesenchymal transition in cancer cells.
Examples
Vimentin is primarily expressed in mesenchymal cells.
Vimentin is primarily expressed in mesenchymal cells.
The researcher observed an increase in vimentin levels during the epithelial mesenchymal transition.
The researcher observed an increase in vimentin levels during the epithelial mesenchymal transition.
We need to check if the sample is positive for vimentin to confirm the cell type.
Vimentin provides the necessary mechanical strength to maintain cell integrity.
Does this specific tumor express vimentin or keratin?
The antibody binds specifically to the vimentin filaments in the cytoplasm.
I wonder if vimentin phosphorylation affects the stability of the cytoskeleton.
I wonder if vimentin phosphorylation affects the stability of the cytoskeleton.
Vimentin serves as a reliable marker for identifying fibroblasts in tissue sections.
The redistribution of vimentin is often associated with increased cell motility.
The redistribution of vimentin is often associated with increased cell motility.