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talin
Talin is a specialized biochemical term referring to a cytoskeletal protein that links integrins to the actin cytoskeleton. It is primarily discussed within the context of cell adhesion, migration, and mechanotransduction, where it acts as a critical molecular bridge that allows cells to sense and respond to the physical properties of their environment.
As a technical term in molecular biology, it is used exclusively in scientific literature and academic discourse. It does not have a colloquial or metaphorical application outside of proteomics and cell biology.
Meanings
Examples
Talin plays a critical role in the activation of integrins.
Talin plays a critical role in the activation of integrins.
The researcher observed how talin links the cell membrane to the actin cytoskeleton.
Does talin expression increase during cell migration?
Does talin expression increase during cell migration?
Talin is essential for the formation of focal adhesions.
We need to analyze the talin binding sites in this protein complex.
The mutation in talin leads to significant defects in cell adhesion.
I wonder if talin interacts directly with vinculin in this specific pathway.
Talin acts as a molecular bridge between the extracellular matrix and the interior of the cell.