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monogenic
This is a technical term used exclusively in genetics, medicine, and biology. It is never used in casual conversation unless the speaker is discussing a specific medical diagnosis or scientific research. It describes a condition where a single gene is responsible for the trait or disorder.
In professional discourse, it is almost always contrasted with polygenic (caused by multiple genes) or multifactorial (caused by a combination of multiple genes and environmental factors). Using "monogenic" in a non-scientific context would be perceived as overly formal or misplaced.
When used in a clinical setting, it implies a predictable pattern of inheritance, such as autosomal dominant or recessive, which distinguishes it from the more complex inheritance patterns of common diseases like type 2 diabetes or hypertension.
Meanings
Examples
Cystic fibrosis is a well known monogenic disorder.
Is this condition polygenic or monogenic in nature?
The researcher focused on identifying the monogenic cause of the rare disease.
I wonder if the patient has a monogenic predisposition to this heart condition.
Monogenic traits are typically easier to map than complex ones.
We need to determine if the mutation is monogenic before starting the trial.
The study highlights the difference between monogenic and multifactorial inheritance.
The study highlights the difference between monogenic and multifactorial inheritance.