glycation
The non-enzymatic reaction where sugar molecules bond to proteins or lipids without the control of an enzyme, often leading to the formation of advanced glycation end-products (AGEs).
Noun
This term is primarily used in biochemistry, dermatology, and medicine to describe a specific chemical process. It carries a negative connotation in health contexts, as it is associated with aging, diabetes complications, and the degradation of structural proteins like collagen. It is distinct from glycosylation, which is an enzyme-controlled, regulated biological process.
As a technical term describing a chemical process, it is treated as an uncountable noun. It refers to the phenomenon itself rather than individual instances of the reaction, meaning it does not typically take a plural form in scientific literature.
Meanings
Examples
School Life
Glycation occurs spontaneously without the need for an enzyme catalyst.
School Life
Related Words
glucoseproteincross-linkingreactiondiabeteshyperglycemiacollagenelastinoxidationstresscarbohydrateaminoacidlysineargininecarbonylaldehydeketonebaserearrangementglycosylationenzymecatalystmetabolismbloodsugarhemoglobinagingsenescencewrinkleskindermisstiffnessinflammationvasculararterykidneynephropathyretinopathyneuropathycomplicationinsulinresistancemodificationbondcovalentstabilitydegradationproteolysisautophagyreceptorRAGEligandcytokineantioxidantchelatorinhibitorpyruvatelactatefructoseribosepentosehexosecaramelizationbrowning