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lesion

tissue damage / wound

/ˈliːʒən/

[C] Countable
pl: lesions

A clinical, sterile term used to describe any abnormal change in the structure of a tissue. Unlike "wound" (which implies an acute break in skin) or "sore" (which suggests pain and inflammation), a lesion is a descriptive category that encompasses everything from a tiny blister to a deep internal tumor. It carries a neutral, diagnostic connotation. In a medical context, it identifies the 'what' and 'where' of a pathology without necessarily assigning a cause or prognosis immediately. It is the preferred term in radiology, dermatology, and neurology to maintain professional objectivity.

💬Casual Conversation

🎬David's car, stuck in traffic after a long day at work.
Eleanor Smith

DID THE DOCTOR CALL ABOUT THAT LESION? I AM STILL SO UPSET.

Eleanor Smith
David Smith
David Smith

Mom, it's fine. Just a benign thing. Nothing to dwell on.

💡
Eleanor, being an overbearing and technologically illiterate mother, uses Caps Lock to express her heightened concern about David's medical 'lesion'. David, her stressed son, tries to downplay the issue and uses the phrasal verb 'dwell on' to tell her to stop focusing on it, reflecting his annoyance with her overprotective nature.

Meanings

Nountissue damage

A region in an organ or tissue which has suffered damage through injury or disease, such as a wound, ulcer, abscess, or tumor.

"The MRI scan revealed a small lesion on the patient's frontal lobe."

Nounwound

A wound or injury to the skin or other tissues of the body.

"Skin lesions can be a symptom of various allergic reactions."

Collocations & Compounds

skin lesion

An area of damaged or diseased tissue on the skin.

The doctor examined the suspicious skin lesion on his arm.

brain lesion

An area of damage or abnormality in the brain.

An MRI scan revealed a small brain lesion.

liver lesion

An abnormal area of tissue found in the liver.

Further tests were needed to determine the nature of the liver lesion.

focal lesion

A lesion that is localized to a specific area.

The biopsy confirmed it was a focal lesion.

pathological lesion

A lesion caused by a disease process.

The pathologist identified the pathological lesion under the microscope.

Etymology

The word 'lesion' comes from the Latin word 'laesio', meaning 'a blow, hurt, or damage'. It entered English in the 17th century, primarily used in medical contexts to describe an injury or abnormality in body tissue.

Related Words

Last Updated: June 8, 2026Report an Error