glucuronide
glucuronide
Noun
pl: glucuronides
This term is used exclusively within biochemistry and pharmacology to describe a specific type of metabolic conjugate. It carries a neutral, technical connotation and is typically found in medical literature, pharmacokinetic reports, and organic chemistry textbooks.
Because it refers to a specific chemical structure, it is used in a precise scientific register. It is rarely encountered in general conversation, appearing instead in discussions regarding drug metabolism, detoxification processes in the liver, and the renal clearance of xenobiotics.
Meanings
Examples
Is this specific metabolite a glucuronide or a sulfate?
Glucuronide conjugation is the primary pathway for eliminating these phenols.
Related Words
glucuronic acidglucuronidationUDP-glucuronosyltransferasemetabolismdetoxificationconjugationmetaboliteliverkidneyexcretionurinebilepharmacokineticspharmacodynamicsdrugxenobioticenzymesubstrateglucosesugarcarbohydrateacidesteretherglycosideglucosidehydrophilicsolubilitypolarityclearancehalf lifebioavailabilityoxidationreductionhydrolysissulfationmethylationacetylationglutathionebilirubinsteroidhormonetoxinphenolalcoholcarboxylic aciduronic acidUDPnucleotidecatalystbiotransformationpharmacologybiochemistryphysiologytoxicologymetabolic pathwayaglyconeglycosylation